The stars play adoptive parents waiting for the mother of what they hope will be their child to give birth while they take an anniversary trip to Italy.

A gay adoption comedy that veers off into travel porn before taking a hard left into dark fish-out-of-water farce, I Don’t Understand You is a lot fresher and more enjoyable than its generic title might suggest. That’s largely because Nick Kroll and Andrew Rannells make such an effortlessly funny and convincing couple that they smooth over the rough transitional patches. It probably also doesn’t hurt that writer-directors Brian Crano and David Craig are a married couple, giving them insight into the foibles of longtime partners who let nothing — not even a pile-up of dead bodies — get in the way of their family goals.

It’s a welcome change, however, that queer parenthood and its attendant anxieties aren’t played for melodrama, instead providing the sweet ballast to what’s primarily a nightmare vacation comedy. Streaming platforms looking for breezy LGBTQ content could do a lot worse.

We never learn much about what either man does for a living, but these are well-heeled guys living in an airy Los Angeles home, flying business class and staying in upscale boutique hotels.

Their 10-year anniversary trip to Italy gets off to a somewhat portentous start when a glop of blood lands on Cole’s shirt soon after they board their flight, from raw meat that a fellow passenger had stored in the overhead bins. But after some momentary confusion from the hotel concierge about two men booking the honeymoon suite is defused, things look up as the eagerly awaited call arrives from expectant mother Candice (Amanda Seyfried), who chooses Dom and Cole to raise the baby boy she’s putting up for adoption.

As they stroll around postcard-pretty Rome, any tension in their relationship appears to melt away, along with apprehension stemming from a painful past experience with attempted adoption. Over a meal in the home of Daniele (Paolo Romano), an old friend of Dom’s father, they learn that he has arranged an anniversary dinner for them at a farmhouse restaurant off the tourist grid outside the Umbrian town of Orvieto. Daniele’s gift to them both of engraved pocket knives seems only mildly disconcerting.

The spiraling disaster of the evening involves vegetarian Cole being coerced into sampling a pizza topped with horsemeat sausage; Dom feeling endangered after misunderstanding the thick accent of Luciana’s son Massimo (Morgan Spector); and the latter’s fiancée Francesca (Eleanora Romandini) becoming hysterical when she stumbles upon what appears to be a scene of bloody mayhem.

There’s some gentle mockery in the script of Americans feeling so secure in their privilege they can walk away from any chaos unscathed, even if that chaos involves a string of (mostly) accidental deaths. One semi-running gag has Dom and Cole — and later a burly gay Italian detective (Fabio Salerno) — gasping in horror over perceived homophobic slurs, even as far more ruinous situations are unfolding. But all this is treated with an appealing buoyancy that makes even the most stereotypical jokes — concerning the inefficiency of Italian law enforcement, for instance — go down easily.

Seyfried is lovely in her brief scenes, indicating the painful process for any woman of giving up her child; and it’s fun to see Spector (who appeared alongside his wife, Rebecca Hall, in Crano’s Permission) going full carbonara with extra cheese as a rugged man of the land.